Actividad cicatrizante de los extractos Metanólicos de Justicia Chlorostachya y Plectranthus Amboinicus mediante ensayos In Vitro de Inhibición de Hialuronidasa y Veneno de Cobra (Naja naja).

Abstract

The Healing Effect of Methanol Extract of Plectranthus amboinicus and Justice chlorostachya was determined by the in vitro inhibition of hyaluronidase and cobra venom (Naja naja), performed at the Laboratory of Phytopharmacy and Instrumental Analysis of the Sciences Faculty of The Escuela Superior Politécnica de Chimborazo. Where it was used different treatments for each plant used, which were: 0.005 g/mL – 0.01 g/mL and 0.02 g/mL of Plectranthus amboinicus flavonic part and Justice chlorostachya for different analysis. White and negative control was used where will be presented the main activity of the trials. The different extracts were obtained by soxhlet extraction and flow from 50 grams of the dried aerial part of the various plants used. The results obtained in the inhibiting hyaluronidase were satisfactory in Plectranthus amboinicus treatments with 82.5% inhibition at doses of 0.02 g/mL and with the Justice chlorostachya treatments lesser extent. In the obtained results for the inhibition of cobra venom the Plectranthus amboinicus treatments were satisfactory compared to the Justice chlorostachya treatments. It is recommended further research on the analysis of inhibition of hyaluronidase about the Justice chlorostachya extracts, using a method to better measure the amount of n-acetylglucosamine released.