Estudio Farmacognóstico y Actividad Cicatrizante del Jatun Quilun Quilun

Abstract

The pharmacognostic study and healing activity of Jatun quilun quilun (Tradescantia zanonia) in mice (Mus musculus), a plant used in Tena as a healing agent for skin cuts, was carried out. Carried out in the Laboratories of: Phytochemistry, Microbiology and Biotherium of the Faculty of Sciences of ESPOCH, investigative-bilbiographic and Experimental methods were applied, with the purpose of contributing to the knowledge, with scientific basis and usefulness in the possible elaboration of phytopharmaceutical products. The hydroalcoholic extract of Jatun quilun quilun was prepared by maceration, and the brown concentrate was obtained with the rotary evaporator. The physical-chemical analysis determined: humidity 90.18 %, ashes 8.64%, pH of 5.69, refractive index 1.353, density 0.998 g/mL, total solids 6.78 g. The presence of alkaloids, tannins, quinones and lactonic groups was evidenced, which supports its use in wound healing. Fifteen mice divided into five groups were used: white, positive control (Lamoderm®), 25% extract, 50% extract and 75% extract, with a wound on the back 1.5 cm long by 2 mm deep. Better results were obtained with the 50% extract, healing the wound 8 days after treatment, verified by macro and microscopic analysis of the healed skin of the mouse; for the analysis of the data obtained, the ANOVA and Turkey test at 5% were applied. It is concluded that the extract of Jatun quilun quilun at 50% has a greater healing activity than Lamoderm®, a product of conventional use. It is recommended to continue with the study of this plant and subsequently develop a phytomedicine.