Formulación y control de calidad de Fotoprotector a base de Myrcianthes hallii y Oreocallis grandiflora

Abstract

The aim of this study was to formulate a photoprotector based on extracts of Myrcianthes hallii and Oreocallis grandiflora, species that were considered because researches carried out have shown that they have healing properties and photoprotective activity, being responsible for these functions the secondary metabolites, especially the flavonoids. As a starting point, quality control was carried out on the plant species, and subsequently phytochemical screening was carried out, identifying metabolites in Oreocallis grandiflora such as: alkaloids, catechins, reducing sugars, saponins, phenolic compounds (flavonoids) and in Myrcianthes hallii : lactones, coumarins, triterpenes and steroids, catechins, reducing sugars, saponins, phenolic compounds (flavonoids), and quinones. Next, extracts were obtained, and 9 formulations were prepared, where parameters were varied such as: the amount of extracts, type and presence of excipients such as beeswax and cocoa butter, which act as emollients; that is, they help moisturise the skin; the amount of stearic acid and propylene glycol provide moisturizing properties. Finally, the physical, chemical and organoleptic parameters established in the INEN NTE 2867 regulation were evaluated, with the results a statistical analysis was carried out to determine which of all the formulations meets the established characteristics, in addition, the SPF (Sun Protection Factor) was determined and microbiological analysis. It was concluded that all the formulations obtained an SPF between 37-49, demonstrating a high photoprotective potential, however, the ideal formulation was 5, which had an SPF of 45.39 and the most appropriate organoleptic characteristics for the presentation of the finished product. It is recommended to propose phytocosmetic formulations with isolated flavonoids.