Insulinoma

Abstract

This research is about Insulinoma which is a pancreatic secreting insulin neuroendocrine tumor, usually infrequent, small, unique, benign and sporadic that presents with hyper insulinemic hypoglycemia and occurs within the fifth decade of life onwards. This originates from the pancreatic beta cells which produces an abnormal regulation in the production of insulin, causing the appearance of the classic triad described by Whipple characterized by signs of hypoglycemia, decreased levels of glycemia and immediate recovery after glucose administration. Its treatment is carried out pharmacologically or surgically, depending on the manifestations and the clinical condition of the patient. It is presented a clinical case of a male patient over 86 years of age who debuted with neuroglycopenic symptoms, presented a quantified hypoglycemia and after intravenous administration of a 10% dextrose solution, there is evidence of a notable clinical improvement of the same. During several months of follow-up, it was confirmed insulinoma diagnosis by octreoscan; so, it is treated in the center of the third level where enucleation plus distal pancreatectomy is performed for the definitive resolution of its pathology. The patient in mention presents an adequate postoperative evolution, symptomatic remission and normal blood glucose levels. Ten days after being discharged, due to comorbidities of the base and pancreatic collection which receives antibiotic therapy, patient presents hemodynamic decompensation and dies.