Determinación del antígeno prostático específico total y libre con ayuda al diagnóstico de alteraciones prostáticas en hombres de 45 a 65 años del GADPCH.

Abstract

The objective of the current research work was to determine the total and free prostate-specific antigen as an aid to the diagnosis of prostatic alterations in men aged 45 to 65 years of GADPCH. This research work is a non-experimental descriptive, including a statistical design through Microsoft Excel that allowed corroborating the sensitivity and specificity of this test which focuses the predisposing risk factors such as: age, family history, alcohol, style of life, type of food and tobacco. The assessment was applied in 100 patients who work in the GADPCH of Riobamba city. The samples were processed in the Clinical and Bacteriological Laboratory of the ESPOCH, “Escuela de Bioquímica y Farmacia de la F acultad de Ciencias” trough the enzyme immunosorbent assay that quantifies the serum levels of the free PSA and the total PSA giving as results of the first test: the 98% of patients are within the normal values and the 2% shows altered values and the second test has the 97% of normal values and the 3% of altered values; taking into account that the most predictive risk factors are the type of feeding: the 12% consume meat products, the 8% has relatives with this pathology, the 13% consume alcoholic beverages 3 times a week, the 4% of the population smokes more than 6 cigarettes a week, and only the 16% has a sedentary lifestyle. It is concluded that the prostate-specific antigen is a useful tool in the early diagnosis of prostatic disorders in men over 45 years, for which it is recommended to visit the doctor at least twice a year to perform routine monitoring, which allows performing the early dignosis of prostatic disorders.