Comparación del efecto cicatrizante de tinturas elaboradas a base de guarango (Caesalpinia spinosa) y sangre de drago (Croton lechleri) aplicados en ratones (Mus musculus)

Abstract

It was the comparison of the he aling effect of dyes, elaborate with guarango ( Caesalpinia spinosa Molina Kuntze) and Drago ́s blood ( Croton lechleri Muell - arg) applied in mice ( Mus musculus ), in the vivariu m of the Escuela Superior Polité cnica de Chimborazo. Tinctures of two plants, wh ich was the control of quality of raw materials and dyes, were obtained by maceration method. We did the experiment in 8 groups of mice, using: G (Guarango ( Caesalpinia spinosa ) 100 %), SD (Dragon ́s blood ( Croton lechleri ) 100%), G1.SD1. (Guarango ( Caesalpi nia spinosa ) and Sangre de Drago ( Croton lechleri ) 50 porcent: 50%) and G2.SD2. (Sangre de Drago ( Croton lechleri ) and Guarango ( Caesalpinia spinosa ) 70%:30%) respectively and as group of controls: B (white), N (negative control), C (positive control wi th cream Lamoderm), E ( positive control with Eterol), topically – administered 100μL of dyes once a day in the wounds, subsequently histopathological analysis was performed. In the quality control of raw materials and dyes the data obtained are within the reference values of the phytochemical screening were saponins, flavonoids, tannins with high evidence. With respect to the healing activity is conclu ded, that the most effective treatment is that of SD1.G1. It healed in 10 days, in the Histopathological Analysis scartissue from all positive control and treatments has been reconstructed to 100% find negative control to 60%. We recommend a commercial pro duct using these dyes for veterinary use.