Determinación de los niveles de Colinesterasa y Evaluación de la presencia de efectos Neurotóxicos en trabajadores expuestos a plaguicidas organofosforados y carbamatos de la parroquia de San Luis

Abstract

The determination of serum cholinesterase was performed and the neurotoxic effects in f armers exposed to organophosphates and carbamates of the communities of San Antonio and Uncle mine in the parish of San Luis, in order to prove whether it influences the habitual use was assessed these toxic levels of cholinesterase enzyme and the prevalen ce of neurotoxic effects on the body. This study was conducted by the socialization of each community, through interviews and observation of workplace farmers, the determination of serum cholinesterase in blood was performed with the technique of Ellman by ultraviolet spectrophotometer and the prevalence of neurotoxic effects by PNF test, which evaluates the mental activity of the Central Nervous System. The result produced a considerable involvement, 48% presenting low values in enzyme activity, 32% were m ale and 16% female, ranging from 30 - 49 years and men 2% of patients have high values in a range of 50 - 59 years. The exposure time in years, in hours and frequency of use is directly proportional; therefore the longer and more frequently exposed low values percentage present and therefore negative effects on health. Finally, by the neurotoxic analysis was obtained, light conditions for neurological disorders, fatigue and mild conditions to psiconeurovegetativas disturbances, irritability and concentration an d memory defects; both men and women. Concluding that about half of subjects had alterations; affected mostly men who are of working age, and that only 8 patients presented clinical, behavioral and neurological disorders. Recommending training continues on Biosafety, poisoning and prevention of diseases associated with pesticide use conditions.