Estudio Clínico de la Actividad Antifúngica del Gel con Tocte, Higo, Dulcamara y Salvia en Niños de la Comunidad Sanjapamba con Malassezia furfur

Abstract

The objective of this research was to prepare extracts of Tocte (Junglans neo tropica), Fig (Ficus carica), Dulcamara (Solanum dulcamara) and Salvia (Salvia officinalis) to determine physical and chemical properties and to prepare a gel with 1% Carbopol and 0.15% of the extracts, essential oils and their application on the face of children with Malassezia furfur fungus and to observe their effect. The ethanolic extracts are prepared by maceration and the essential oils were purchased. The gel is obtained by mixing 1% Carbopol in distilled water and 0.15% of the extracts of Tocte, Fig, dulcamara and the essential oil of Salvia. The selection of 60 children from the Sanjapamba Community School in the Province of Chimborazo was determined with a positive KOH test. The application of the gel was carried out every 24 hours and 48 hours for 15 days to groups of 24 children for each time respectively, observing positive results with progressive decrease of the spots caused by the fungus Malassezia furfur. It was determined that the application of the gel every 24 hours for 15 days is the most appropriate, being proved by the analysis of variances and the Tukey test at 5% with a mean of elimination of the fungus stain 96.87% and with the control (Neo-nystasolone) gave 95.15%.