Obtención de resina de cbd a partir de Cannabis sativa L. (cannabis no psicoactivo) como promotor en la elaboración de gomitas antiestrés

Abstract

The main objective of this research study was to focus on obtaining CBD resin from non- psychoactive Cannabis to produce anti-stress gummies through quantitative research with an experimental approach. The raw material was collected at the Instituto Superior Tecnológico Jatun Yachay Wasi. For the extraction of the resin, its conformity with the Ministerial Agreement 148 of the Ministry of Public Health, and with the resolution of the National Agency of Regulation, Control and Sanitary Surveillance: ARCSA-DE-002- 2021-MAFG, was verified. Then we proceeded to the manufacture of the anti-stress gummies according to compliance with the NTE INEN 2217:2012 standard. In the extraction process, dried Cannabis sativa L. was used, selecting the appropriate amount of cannabis for three extractions. After weighing, the sample was washed and decarboxylated. In the first extraction, 96% ethanol was used, in the second extraction process, hexane was chosen, and finally, it was decided to use an 80% hydroalcoholic mixture as the reference solvent. The results obtained in this study showed that CBD resin can be obtained effectively from non-psychoactive cannabis, reflecting that hexane was the solvent with the best performance and cannabinoid extraction capacity, obtaining a percentage of 10.85% in the process. However, due to its disadvantages as a hydrocarbon, it was decided to use the extract obtained from ethanol, since it obtained a 10.14% extraction rate, while the hydroalcoholic mixture reached 7.43%. It was demonstrated that the resin obtained complies with national regulations in terms of cannabinoid content and can be used for the production of anti-stress gummies, since 13.6% of humidity was obtained according to the NTE INEN 265 standard, finally, the microbiological analysis verified the absence of microorganisms.