Seguimiento de Farmacovigilancia Post – Inmunización contra Covid – 19 en la Escuela Dr. Mariano Borja, del Cantón Colta de la Provincia de Chimborazo

Abstract

The aim of this research work was to carry out a post immunization pharmacovigilance follow-up against COVID-19 in Mariano Borja school in Chimborazo province, by means of an observational, descriptive and cross-sectional study. The study population consisted of 320 schoolchildren who had already been immunized against COVID-19 and the study was carried out in two phases: the child population was identified, data collection matrices and surveys were elaborated. The results showed that, after vaccination, the students presented some adverse effect such as fever (28.82%), pain at the puncture site (84.74%) and to treat these adverse reactions, paracetamol was administered (49.72%). In the first dose, 10.17% presented serious reactions such as allergies and went to the pharmacy to receive medication to treat the discomfort caused by the vaccine, while in the second dose the percentage of adverse reactions decreased to 3.45% and in the third dose, the students did not present any effect of the vaccine; therefore, it was relevant to fill out the pharmacovigilance forms. Regarding allergies, 2.26% of the students presented urticaria and 1.69% presented anaphylaxis, so the students required medical examination and pharmacological treatment. It was concluded that the adverse effects produced by the vaccines are due to the weak immune system of the students, since none of them presented re-infection by the virus, which showed the high rate of efficacy of the vaccines. It is recommended to establish a committee whose function be the pharmacovigilance of vaccines in children which should update information and, in case of anomalies, notify the corresponding system.