Evaluación de la Actividad Antiinflamatoria de la Mezcla de Extractos Fluidos de Jengibre (Zingiber officinale), Tomillo (Thymus vulgaris L.), Romero.

Abstract

"The research aims to evaluate the antiinflammatory activity of the mixture of extrats of Ginger (Zingiber officinale), Thyme (Thymus vulgaris L.) and Rosemary (Rosmarinus afficinalis) by Scientific research methods, Hypothctical-Deductive and Analytical- Experimental, using different doses in order to find the most appropriate to test their effectiveness, as an alternative o the use of anticinflammatory drugs because there is a tendeney to use natural products.

The antiinflammatory effect was measured in 15 rats (Rattus novergicus), which were injected with 0,5% carragcenan into the plantar region causing inflammation, were subjected to $ treatments, with T1, T2 and T3 for formulations 1, 2, 3 respectively, T4 a control group that received only the vehicle distilled water, TS a group that reccived the anticinflammatory Naproxen sodium 12,40 mg/Kg.

Administered orally using a cannula in the following dosages: Formulation 1 (Ginger 28,6; 429 Thyme; Rosemary 28,6) mg/Kg; Formulation 2 (14,3 Ginger; Thyme 85,8; Rosemary 572) mg/Kg and Formulation 3 (Ginger 14,3; 42,9 Thyme; Rosemary 28,6) mg/Kg, measured volumes of inflammation from O up to 12 hours found a decrease in the rate of edema formation.

Rates were calculated cach 2 hours and found that there was a statistically significant difference between treatment groups and control group (p <0, 05). The antiinflammatory effect is increasingly obtained: TI>T3>T2, We conclude that the formulation 2 showed effective anti-inflammatory Naproxen sodium than during the twelve hours of testing, from the twelfih hour the swelling goes down progressively. It is recommended to develop the phytomedicine of the formulation 2 to facilitate storage and administration."