Enfermedad trofoblástica gestacional

Abstract

The objective of this titling work was to present the presentation of gestational trophoblastic disease and the importance of detection, treatment and follow-up to avoid reaching malignancy which has become a challenge for health personnel. Gestational trophoblastic disease is due to a highly abnormal development of placental trophoblastic tissue, consisting of benign and malignant disorders, within which hydatidiform mole is the highest incidence, in its development several factors intervene within which age, molar pregnancy previous as well as habits influence a large percentage. Hydatidiform mole constitutes excessive trophoblastic proliferation in addition to abnormal embryonic development being completely or partially differentiated genetically by its diploid and triploid karyotype respectively. The diagnosis is based on a multifactorial approach that constitutes the clinical characteristics, the quantitative determination of human chorionic gonadotropin beta, abdominal or transvaginal ultrasound, and is confirmed through the pathological and immunohistochemical study, in addition to cytogenetic techniques and analysis. of the DNA that has allowed to identify and differentiate the complete and partial molar pregnancy. The treatment is based on expiratory curettage prior to mechanical cervical dilation and under ultrasound guidance, in patients with satisfied parity hysterectomy is the best option. Surveillance is very important and Follow-up to avoid reaching a gestational trophoblastic neoplasm after a molar pregnancy.