Análisis del uso de antibióticos en pacientes con Covid-19 en la unidad de cuidados intensivos del Hospital General Docente Ambato

Abstract

The aim of this research was to implement an analysis of the antibiotics used in patients with Covid-19 at the Intensive Care Unit of the Hospital General Docente Ambato. A quali-quantitative analysis was carried out by reviewing the clinical records of patients hospitalized during November 2020 to January 2021, developing a pharmacotherapy monitoring chart in order to identify the antibiotic therapy used and recognize the antibiotics used, frequency, duration and dose administered. It was obtained as a result that the most frequently used antibiotics were carbapenems with 27.12%, in this group the use of meropenem stood out, followed by penicillins, especially piperacillin and tazobactam with 23.22% and finally, the polymyxins, in this group, colistin is found with 16.7%. Regarding drug interactions, these were not directly evidenced in the medical records, however, when reviewing the bibliography, it was determined that concomitant use with other medications can cause interactions that have different severity, hence the importance of the pharmacist at the time of preventing this onset. With regard to adverse effects, signs of inflammatory responses, febrile symptoms and leukocytosis were identified. It was concluded that despite the fact that its transmitting agent SARS-CoV-2 is a virus, the use of antibiotics is essential since they play an important role in the recovery of the patient because during their hospital stay they usually acquire nosocomial infections in which cases it exists confirmation or high suspicion of a coinfection or secondary bacterial infection, that is why it is inevitable to consider the prescription of antibiotic treatment. It is recommended to continue with the corresponding sanitary measures and to continue with the security protocol that has been currently being used in the medical center.