Cirrosis hepática autoinmune

Abstract

In the current work, a 57-year-old male patient with nonspecific symptoms of one year of evolution, treated in different health units, is described since January 2018. He presents jaundice treated as outpatient treatment on several occasions when he presents with acute decompensation and there is evidence of elevated hepatic markers; it is diagnosed as acute type A clinical hepatitis, however recurrence, so it is hospitalized again and several examinations are made when other pathologies are ruled out. It is decided to perform a liver biopsy in which the diagnosis of hepatitis is reached autoimmune and immunosuppressive treatment is initiated with an adequate response but for the delay of diagnosis. The patient already shows signs of cirrhosis, sequential endoscopies are indicated, in spite of having established prescribed therapy for this disease, the patient dies due to rupture of esophageal voice, which is the most common complication of the cirrhosis to wich his pathology had evolved. Autoimmune hepatitis, being a relatively rare pathology with a prevalence of 11,6-17 cases per 100,000 inhabitants and also being more frequent in women. It is not taken as a suspected diagnosis in this patient in the first place, as its clinical picture is recurrent the diagnosis should be based on biochemical tests (absence of viral hepatitis markers), immunological tests (including the detection of autoantibodies) as well as histological characteristics, as morbidity and mortality. In the case of cirrhosis, acute liver failure, and variable transplant-free survival is necessary to always take into account this clinical diagnosis within our differential table in the presence of nonspecific symptoms of liver pathology.