Hipertiroidismo secundario a enfermedad trofoblástica gestacional

Abstract

The current degree work focuses on the study of a clinical case of a 17-year-old female patient, with blood type B RH (+), without relevant pathological history, who attended the consultation due to transvaginal bleeding in scarce amount and pain at the level of hypogastrium, considered as hemorrhage of the first trimester for which the differential diagnosis is made between the three causes of this bleeding, Abortion, Ectopic Pregnancy, and Gestational Trophoblastic Disease. She is admitted to the gynecology service of H.P.G.D.R. where a series of examinations were carried out: qualitative and quantitative B-HCG whose results were positive, TSH-T3-T4, the same ones that presented diminished TSH values and high values for T4, indicative for subclinical hyperthyroidism, also presents transvaginal ECO that reports Gestational trophoblastic disease. Confirmed the diagnosis of Molar Pregnancy, by Echo and by results of B-HCG, proceeds to perform uterine emptying and subsequent control. Due to the persistence of remains a second complementary curettage is performed. The follow-up of the patient was carried out, based on the quantification of B-HCG periodically, the same ones that were gradually decreasing, in the same way, the thyroid profile was periodically quantified, and the same ones that began to descend without needing clinical treatment. The objective of this clinical case is to make a bibliographic review of this pathology and its relationship with hyperthyroidism, establishing the symptoms and signs that help to make a diagnosis and timely treatment, as well as the behavior to be followed after uterine emptying, to control recurrence and prevention or timely diagnosis of choriocarcinoma. The support material was used to help the knowledge of the disease and the reduction of morbidities with timely treatment.